Environmental or self-antigens and homotypic interactions trigger BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other alerts from the microenvironment and growing the activation of anti-apoptotic and proliferation pathways. Serious lymphocytic leukemia is usually a properly-described lymphoid neoplasm with very heterogeneous biological and scienti... https://carolc221rft7.loginblogin.com/profile